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Intracervical Insemination (ICI) Explained: What to Know?

  • 5 min read

Article Medically Reviewed By:Sarah Marsh, RN, CNM, MSN, MPH

It’s such an exciting time in your life when you first decide you’re ready to start a family. Maybe you’re ready to solo-parent, or maybe you and your partner look at each other one day and say, “Yes, let’s do this!”. You might expect to see a positive pregnancy test when your next period is due. Because you tried…a lot. Then, month after month, your heart starts to hurt, and you get a little depressed because it’s not happening, and you have no idea why. You are not alone. The fact is, most people really don’t understand how their reproductive system works, until they start trying to figure out why it’snot working. 

If you’ve been struggling to get pregnant, hearing that there’s a simple way to increase your chances of conceiving - without having to inject yourself with drugs, or visit the doctor’s office for a pricey procedure - sounds almost too good to be true, right? Well, there is a way to boost your chances at conception right in the comfort of your own home. It’s called Intracervical Insemination (ICI). 

ICI is one of the oldest and most common insemination procedures available. It’s a great first step for many couples who want to do all they can on their own before moving on to fertility treatments. Doing everything they can at home may help them move confidently on to next level procedures, which can be expensive, often invasive, and time consuming. And when approaching that 12 month definition of “infertility”, trying at home ICI with a syringe often counts as “trying” according to many health insurance providers. 

What is intracervical insemination?

Intracervical Insemination (ICI) is the process of transferring semen or ejaculate directly into the female reproductive tract, right at or near the cervical opening – which is basically the door to the uterus. 

How do you get the semen to the cervix with ICI? You can do this either at home or at a doctor’s office. At home, you can use a specially designed syringe, like Mosie, to transfer the sperm. At the doctor’s office, often a catheter (thin, flexible tube) with a syringe attached to the end of it, is used to deposit sperm to the cervix.

How does ICI work?

Timing is key when doing Intracervical Insemination (ICI). It starts with understanding your ovulation cycle.

Typically, ovulation happens once a month, when a mature egg is released from one of the ovaries. Many people think that the egg gets fertilized in the uterus or the ovaries, which isn’t typically the case. Fertilization usually happens in the Fallopian tubes, which connect the ovaries to the uterus.

Diagram of Female Reproductive Anatomy

Sperm can survive inside a biologically female reproductive tract for 48 to 72 hours. Outside of the body, sperm can only survive up to an hour.  (Please note that defrosted donor sperm may have a shorter life span and when using frozen sperm you’ll want to ask your sperm bank about their potency lifespan once transferred to your body.

So, you’ll want to have the little swimmers start their journey upstream to the Fallopian tubes before ovulation occurs. That way the sperm will be ready and waiting to fertilize the egg. 

With ICI, you can give sperm a little jump start, by using a syringe, like Mosie, to deliver the sample right at or near the cervical opening. From there the sperm travels up to the uterus, and into the Fallopian tubes. After depositing the sperm at the cervix, you should remain lying down, preferably with a pillow under your hips, for 15 to 30 minutes, so gravity can help the sperm on their journey.

If fertilized, the egg, now called a zygote, starts to divide into multiple cells through a process called mitosis, and then makes its way to the uterus - a journey that takes about 3 or 4 days after fertilization.  Once the fertilized egg gets to the uterus, it will hopefully implant and begin to develop into anembryo.

If the egg isn’t fertilized, or doesn’t attach and develop inside the uterus, your period will start about two weeks later, shedding the uterus lining in preparation for a new cycle, and another chance to try again.

Who usually tries intracervical insemination?

A short list of candidates for ICI are:

  • Couples with unexplained infertility 
  • Those with cervical mucus problems
  • Those with semen issues like low motility or having a low sperm count
  • Those with impotence or who struggle with premature ejaculation or intimacy issues 
  • Single Mother’s By Choice 
  • LGBTQ+ families
  • Those with vaginismus or vulvadynia or for whom sex is painful or not appealing
  • People with a disability. In this situation, the biologically male must be able to achieve orgasm and/or it must be safe for the biologically female to be pregnant
  • Co-parents not interested in sex with each other
  • People looking for an option to try at home before pursuing IUI 

Who is not a good candidate for ICI? Intracervical insemination is only an option for people with a healthy uterus, who are ovulating, and at least one functioning Fallopian tube. 

How much does ICI usually cost?

The only cost of doing ICI at home on your own, is for the insemination kit and potentially an ovulation predictor kit. One of the most popular options for home insemination is the Mosie Kit, which comes with two MD & RE endorsed, ergonomically-designed insemination syringes, a specimen collection cup, and educational instructions on how to use Mosie. A Mosie Kit costs $89 ($44.50 per attempt) and is currently available exclusively atwww.mosiebaby.com.

What's the average success rate of ICI?

Much like male/female intercourse, your age, if you’re using fertility medications, or if you have any underlying medical conditions – all affect the success rates of an ICI. 

That said, the average success rate for intracervical insemination is between 10% and 15% per attempt, and that rate increases to nearly 38% after six tries. 

How is ICI different from IVF or IUI?

Intracervical insemination (ICI), Intrauterine Insemination (IUI), and in vitro fertilization (IVF), are all ways to help people get pregnant without sex. IUI and IVF – are medical procedures that are done by a doctor, at a fertility clinic or surgery center. ICI can be a do-it-yourself process, done at home, with a specially designed syringe, like Mosie

ICI delivers sperm to the cervical opening, whereas IUI delivers sperm directly to the uterus. IVF is a completely different process. 

The IVF procedure starts with the biologically female person taking inject-able hormones for weeks, so that several eggs mature at the same time. Then a doctor surgically retrieves the eggs. In a lab, the eggs are mixed or injected with “washed sperm” – with the hopes that they will fertilize. A few days after the eggs fertilize, and become an embryo, a doctor transfers one of more of the embryos directly into the uterus. That’s where an embryo will hopefully implant, and begin to mature inside the uterus. 

ICI is the simplest and least expensive of the three techniques. However, there are cases where IVF is the only viable option. For example, if a your Fallopian tubes are tied, burned or damaged, or if you can’t produce enough sperm through ejaculation. Also, with IUI, and IVF, the sperm is screened and cleaned before being used, which is sometimes necessary with certain types of male factor infertility.

How does Mosie compare to intracervical insemination?

The Mosie kit is designed to allow you to do Intracervical Insemination (ICI) at home. For many, this is the preferred method, since in most cases, it’s unnecessary to involve a doctor, and pay additional fees, for such a simple procedure. 

If you have any questions whether this procedure is right for you, please do check with your doctor. And if we can help support you on your journey to conceive, reach out to us. We love hearing from folks in the Mosie community!

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